BONE ENGINEERING-BIOLOGICAL MATERIALS AND BONE MORPHOGENETIC PROTEINS-
نویسندگان
چکیده
منابع مشابه
Pdf bone morphogenetic proteins
Human bmp-2 ELISA Kit Bmp2 recombinant antibodyAbstract. Bone morphogenetic proteins BMPs are multi-functional growth factors belonging to the transforming growth factor ß superfamily. Family members are.ABSTRACT. The BMPs bone morphogenetic proteins are a group of related proteins originally identified by their presence in bone-inductive extracts of de.Molecular cloning of bone morphogenetic p...
متن کاملSignal transduction and biological functions of bone morphogenetic proteins.
Bone morphogenetic proteins (BMPs) are multi-functional growth factors and belong to the transforming growth factor beta (TGFbeta) superfamily. The roles of BMPs in embryonic development and cellular functions in postnatal animals have been extensively studied in recent years. Signal transduction studies have revealed that Smad1 and 5 are the immediate downstream molecules of BMP receptor and p...
متن کاملBone morphogenetic proteins and tissue engineering: future directions.
As long as bone repair and regeneration is considered as a complex clinical condition, the administration of more than one factor involved in fracture healing might be necessary. The effectiveness or not of bone morphogenetic proteins (BMPs) in association with other growth factors and with mesenchymal stem cells in bone regeneration for fracture healing and bone allograft integration is of gre...
متن کاملBone morphogenetic proteins in human bone regeneration.
Recently, the first clinical reports on bone regeneration by two recombinant human bone morphogenetic proteins (rhBMPs), BMP-2 and BMP-7 (also named osteogenic protein-1, OP-1) have been published (1-4). Although both BMPs were able to support bone regeneration, a significant variation in individual response was observed with both proteins. Animal studies and laboratory experiments reveal a num...
متن کاملSulfated polysaccharides enhance the biological activities of bone morphogenetic proteins.
Bone morphogenetic proteins (BMPs), which have been shown to be heparin-binding proteins, induce osteoblast differentiation in mesenchymal cells. In the present study, we examined the effects of heparin on the BMP activities in C2C12 myoblasts. Heparin dose dependently enhanced the osteoblast differentiation induced by not only homodimers of BMP-2 or BMP-4 but also heterodimers of BMP-2/6 or BM...
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ژورنال
عنوان ژورنال: Phosphorus Research Bulletin
سال: 2004
ISSN: 0918-4783
DOI: 10.3363/prb1992.17.0_51